AKC Registration vote!

As many of you know, the DCA has mailed out ballots to its members asking for a "yes" or "no" vote on supporting AKC registration of the Low Uric Acid Dalmatians (descendants of the Backcross Project). We know that there are still some questions that people have and that there are some misconceptions about the LUA Dals. For some good up-to date information on the important issues and answers to questions that have been asked, please take a look at the "Frequently Asked Questions" that have just been posted to the LUA Webpage. Two ways to get there:
www.luadalmatians.com
This is the website developed to provide information on the Low Uric Acid Dalmatian program. A wealth of information is provided along with photos and pedigrees. From that homepage, you can click on the flashing "New FAQ" button.
www.luadalmatians.com/REGISTRATIONFAQ.html
This will take you directly to the FAQ's

Permission to Cross-post.

DCA give inaccurate info to it's members!

I read the Con Introductory Statement on the DCA website with interest. The
following statement, however, puzzled me:

"The backcross experiment proved only that the Dalmatians that received the
gene for typical canine-uric acid metabolism do convert uric acid to
allantoin before excretion. At the time of the original experiment, it was
commonly assumed that uric acid was the cause or at least the primary cause
of urate stone formation. The leading US canine stone experts, Drs. Bartges
and Osborne, do not support that view. . . ."

This is in conflict with what Drs. Osborne, Bartges, Lulich, Unger,
Thumchai, Koehler, Bird, and Felice wrote:

"Regardless of the theory proposed for nucleation and nidus formation, an
essential requirement is supersaturation of urine with a urolith-forming
crystalloid. A crystal nidus cannot be formed if urine is undersaturated
with the crystalloid in question." from CANINE and FELINE NEPHROLOGY and
UROLOGY, Carl A. Osborne and Delmar R. Finco, editors --Williams & Wilkins,
1995, Chapter 41 -- Canine and Feline Urolithiasis: Relationship of
Etiopathogenesis to Treatment and Prevention (Carl A. Osborne, Jody P.
Lulich, Joseph W. Bartges, Lisa K. Unger, Rosama Thumchai, Lori A. Koehler,
Kathleen A. Bird, Lawrence J. Felice -- Page 809 -

So, according to Osborne, et al, without urine supersaturated with uric
acid, urate stones cannot form. The chapter quoted above does say
elsewhere that other factors may influence the size of the stones, but only
if the stones first form in supersaturated urine.

As the Cons agree with the Pros, the Dalmatians that receive the gene for
typical canine-uric acid metabolism do convert uric acid to harmless
allantoin. This prevents uric acid levels from reaching a state of
supersaturation (except in cases of liver shunts--not common in Dals--or
reaction to medication). No stones can, therefore, start to form. Any
other factors that might affect the size or tendency to block have nothing
to work on.

Yes, other factors may play a part in whether or not a dog might actually
block, but when will they be identified? Will they involve one gene or a
number of genes? Can they be bred out? Not everything can. One genetic
factor that strongly influences whether or not a Dalmatian will block with
stones is whether it is a dog or a bitch. Try breeding away from that one!

We have identified one gene, mutated in the breed, that can be replaced by a
working version. Everyone agrees that doing so does effectively lower the
levels of uric acid. This will avoid the state of supersaturation that
expert opinion says is essential to the formation of urate stones and
crystals.

We can return an unmutated form of this gene to our Dals without losing
breed type--witness Fiona's success in Britain where she can compete on
equal terms with other Dals! I hope the members of the DCA will agree that
type should be determined in the breed ring where everyone can see it.

Sarah Morgan

STONE FORMERS

ANOTHER TWO STONE FORMERS ON THE BDC FORUM!

Gosh it's so rare isent it!!!!!! (I think not)

See us on Facebook

Dalmatians with the low uric acid gene

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ANOTHER STONE FORMER!

Another stone former this time on dalnet list!
How sad that our clubs refuse to acknowledge
just how prevalent this health problem is!

Bringing in problems!?

A close friend said to me at Crufts "Do you no you could be introducing HD into our breed! Pointer have terrible hip problems!"
Another case of myth!!!

THIS IS FROM THE BVA WEBSITE.

The Breed Mean Score (BMS) represents a global mean of the scores of all dogs of that breed that have been through the Hip Dysplasia Scheme up until 31st October
2010. The Breed Median Score has been calculated from data recorded on the Kennel Club’s electronic registration database, up until 31st October 2010. The 5-year mean is the mean of all hip scores recorded on the Kennel Club’s registration
database between 1st November 2005 and 31st October 2010.

Pointer Breed mean score 11. Median 9. 5 year Median 11.

Dalmatian Breed mean score 11. Median 10. 5 year Median 11.


Seems the pointer fairs a little better than the Dals!!!

So what is the problem???

Wendy (in France) will be mated June 2011

Wendy - STOCKLORE FORREST WINDSONG [Uu] (Sire: UKC CH Stocklore Top Spot X Dam: CH Stocklore Vilia Forrest.
Will be mated JUNE 2011 :-)
The puppies will be FCI reg.
Please contact:
Dominique Vincent at dpvincent@orange.fr
or visit his website at:
http://www.dalmatien-mon-ami.fr/