Tyrodal is the pioneer kennel to introduce the gene for NORMAL URIC ACID. into the UK. Todate we have 27 Dalmatians in Europe that carrie the NUA gene To establish an healthier future for this wonderful breed!
Tuesday, September 13, 2011
Tuesday, August 23, 2011
I am so grateful to you all for the good wishes many of you have sent to Fiona and me
On her CC award.
However I am truly saddened by the few 'hate' mail I have also received. Dog World
phoned me this morning to tell me they had also received similar regarding Fiona,
they told me one even said she "moves like a pointer" I am appalled by some of
the people we have in our breed!!!! Fiona will continue to speak for herself!
If Fi moved like a pointer, she would not have been able to have done the miles & miles of road & mountain work she as been doing with our horses! (she's a natural by the way) and is obviouse by her fitness, compared to the bitches in the ring with NO second thigh!!
On her CC award.
However I am truly saddened by the few 'hate' mail I have also received. Dog World
phoned me this morning to tell me they had also received similar regarding Fiona,
they told me one even said she "moves like a pointer" I am appalled by some of
the people we have in our breed!!!! Fiona will continue to speak for herself!
If Fi moved like a pointer, she would not have been able to have done the miles & miles of road & mountain work she as been doing with our horses! (she's a natural by the way) and is obviouse by her fitness, compared to the bitches in the ring with NO second thigh!!
Monday, August 22, 2011
Up-date
Sally and Merlin have just recently been hip and elbow scored.
their registration is being processed, they have both now been assessed
by 2 championship judges & deemed typical of the breed.
Merlin will be shown by Liz Sampson.
Sally (pictured) however is a little small for our showring! She is very much
American in type. So she is busy just enjoying life! but you can see
her on Liz's website.
Wednesday, July 13, 2011
AT LAST! AKC WILL REGISTER NUA DALMATIANS
At the AKC Board meeting this week, the AKC unanimously decided to
authorize AKC Staff to develop, in consultation with DCA, procedures for
the registration of the LUA Dalmatians. These dogs will have a letter
indicator as part of the registration number. There will be more
details available later, and the official AKC minutes will be published
in about a week
authorize AKC Staff to develop, in consultation with DCA, procedures for
the registration of the LUA Dalmatians. These dogs will have a letter
indicator as part of the registration number. There will be more
details available later, and the official AKC minutes will be published
in about a week
Wednesday, June 1, 2011
AKC Registration vote!
As many of you know, the DCA has mailed out ballots to its members asking for a "yes" or "no" vote on supporting AKC registration of the Low Uric Acid Dalmatians (descendants of the Backcross Project). We know that there are still some questions that people have and that there are some misconceptions about the LUA Dals. For some good up-to date information on the important issues and answers to questions that have been asked, please take a look at the "Frequently Asked Questions" that have just been posted to the LUA Webpage. Two ways to get there:
www.luadalmatians.com
This is the website developed to provide information on the Low Uric Acid Dalmatian program. A wealth of information is provided along with photos and pedigrees. From that homepage, you can click on the flashing "New FAQ" button.
www.luadalmatians.com/REGISTRATIONFAQ.html
This will take you directly to the FAQ's
Permission to Cross-post.
www.luadalmatians.com
This is the website developed to provide information on the Low Uric Acid Dalmatian program. A wealth of information is provided along with photos and pedigrees. From that homepage, you can click on the flashing "New FAQ" button.
www.luadalmatians.com/REGISTRATIONFAQ.html
This will take you directly to the FAQ's
Permission to Cross-post.
Saturday, May 28, 2011
DCA give inaccurate info to it's members!
I read the Con Introductory Statement on the DCA website with interest. The
following statement, however, puzzled me:
"The backcross experiment proved only that the Dalmatians that received the
gene for typical canine-uric acid metabolism do convert uric acid to
allantoin before excretion. At the time of the original experiment, it was
commonly assumed that uric acid was the cause or at least the primary cause
of urate stone formation. The leading US canine stone experts, Drs. Bartges
and Osborne, do not support that view. . . ."
This is in conflict with what Drs. Osborne, Bartges, Lulich, Unger,
Thumchai, Koehler, Bird, and Felice wrote:
"Regardless of the theory proposed for nucleation and nidus formation, an
essential requirement is supersaturation of urine with a urolith-forming
crystalloid. A crystal nidus cannot be formed if urine is undersaturated
with the crystalloid in question." from CANINE and FELINE NEPHROLOGY and
UROLOGY, Carl A. Osborne and Delmar R. Finco, editors --Williams & Wilkins,
1995, Chapter 41 -- Canine and Feline Urolithiasis: Relationship of
Etiopathogenesis to Treatment and Prevention (Carl A. Osborne, Jody P.
Lulich, Joseph W. Bartges, Lisa K. Unger, Rosama Thumchai, Lori A. Koehler,
Kathleen A. Bird, Lawrence J. Felice -- Page 809 -
So, according to Osborne, et al, without urine supersaturated with uric
acid, urate stones cannot form. The chapter quoted above does say
elsewhere that other factors may influence the size of the stones, but only
if the stones first form in supersaturated urine.
As the Cons agree with the Pros, the Dalmatians that receive the gene for
typical canine-uric acid metabolism do convert uric acid to harmless
allantoin. This prevents uric acid levels from reaching a state of
supersaturation (except in cases of liver shunts--not common in Dals--or
reaction to medication). No stones can, therefore, start to form. Any
other factors that might affect the size or tendency to block have nothing
to work on.
Yes, other factors may play a part in whether or not a dog might actually
block, but when will they be identified? Will they involve one gene or a
number of genes? Can they be bred out? Not everything can. One genetic
factor that strongly influences whether or not a Dalmatian will block with
stones is whether it is a dog or a bitch. Try breeding away from that one!
We have identified one gene, mutated in the breed, that can be replaced by a
working version. Everyone agrees that doing so does effectively lower the
levels of uric acid. This will avoid the state of supersaturation that
expert opinion says is essential to the formation of urate stones and
crystals.
We can return an unmutated form of this gene to our Dals without losing
breed type--witness Fiona's success in Britain where she can compete on
equal terms with other Dals! I hope the members of the DCA will agree that
type should be determined in the breed ring where everyone can see it.
Sarah Morgan
following statement, however, puzzled me:
"The backcross experiment proved only that the Dalmatians that received the
gene for typical canine-uric acid metabolism do convert uric acid to
allantoin before excretion. At the time of the original experiment, it was
commonly assumed that uric acid was the cause or at least the primary cause
of urate stone formation. The leading US canine stone experts, Drs. Bartges
and Osborne, do not support that view. . . ."
This is in conflict with what Drs. Osborne, Bartges, Lulich, Unger,
Thumchai, Koehler, Bird, and Felice wrote:
"Regardless of the theory proposed for nucleation and nidus formation, an
essential requirement is supersaturation of urine with a urolith-forming
crystalloid. A crystal nidus cannot be formed if urine is undersaturated
with the crystalloid in question." from CANINE and FELINE NEPHROLOGY and
UROLOGY, Carl A. Osborne and Delmar R. Finco, editors --Williams & Wilkins,
1995, Chapter 41 -- Canine and Feline Urolithiasis: Relationship of
Etiopathogenesis to Treatment and Prevention (Carl A. Osborne, Jody P.
Lulich, Joseph W. Bartges, Lisa K. Unger, Rosama Thumchai, Lori A. Koehler,
Kathleen A. Bird, Lawrence J. Felice -- Page 809 -
So, according to Osborne, et al, without urine supersaturated with uric
acid, urate stones cannot form. The chapter quoted above does say
elsewhere that other factors may influence the size of the stones, but only
if the stones first form in supersaturated urine.
As the Cons agree with the Pros, the Dalmatians that receive the gene for
typical canine-uric acid metabolism do convert uric acid to harmless
allantoin. This prevents uric acid levels from reaching a state of
supersaturation (except in cases of liver shunts--not common in Dals--or
reaction to medication). No stones can, therefore, start to form. Any
other factors that might affect the size or tendency to block have nothing
to work on.
Yes, other factors may play a part in whether or not a dog might actually
block, but when will they be identified? Will they involve one gene or a
number of genes? Can they be bred out? Not everything can. One genetic
factor that strongly influences whether or not a Dalmatian will block with
stones is whether it is a dog or a bitch. Try breeding away from that one!
We have identified one gene, mutated in the breed, that can be replaced by a
working version. Everyone agrees that doing so does effectively lower the
levels of uric acid. This will avoid the state of supersaturation that
expert opinion says is essential to the formation of urate stones and
crystals.
We can return an unmutated form of this gene to our Dals without losing
breed type--witness Fiona's success in Britain where she can compete on
equal terms with other Dals! I hope the members of the DCA will agree that
type should be determined in the breed ring where everyone can see it.
Sarah Morgan
Friday, May 20, 2011
STONE FORMERS
ANOTHER TWO STONE FORMERS ON THE BDC FORUM!
Gosh it's so rare isent it!!!!!! (I think not)
Gosh it's so rare isent it!!!!!! (I think not)
Subscribe to:
Posts (Atom)